Technology Opportunities

BGN (42)
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NOVEL COMPOUNDS TO TREAT ANTIBIOTIC-RESISTANT CLINICAL ISOLATED PATHOGENS (Tel Hashomer)
Novel compounds to treat antibiotic-resistant clinical isolated pathogens Israel Nisan, Noa Tejman Yarden, Yaakov Davidov, Galia Rahav , Sheba Medical Center Categories Antibiotics, composition, drug resistant, infection disaeses, Development Stage Pre-clinical Patent ...
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Novel fluoroquinolone-aminoglycoside hybrid antibiotics (Technion)
Bacterial resistance to antibiotics plays a major role in today’s medical world. A series of new hybrid antibiotics containing fluoroquinolone and aminoglycoside antibiotics were designed, synthesized and their antibacterial activities were determined. This combination yielded a new ...
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Novel molecule based on aPC/EPCR PAR1 for the Treatment of Neuroinflammatory Diseases (Tel Hashomer)
Novel molecule based on aPC/EPCR PAR1 for the Treatment of Neuroinflammatory Diseases Prof. Chapman, Dr. Maggio, Dr. Shavit Stein Sheba Medical Center, Israel Categories Composition, Drug, Neuro-Inflammation, Neurodegeneration, Parkinson, Alzheimer , Multiple Sclerosis Development ...
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Novel Molecules for the Treatment of Disorders that Benefit from Lithium Treatment (BGN)
Inositol monophosphatase (IMPase) is a key enzyme in regulating the phosphatidylinositol (PI) signaling system. It catalyzes the dephosphorylation of myo-inositol monophosphates to free myo-inositol. Lithium salts (Li), the drug of choice for the treatment of bipolar disorder (manic-depressive ...
Scientific Contact: Galila Agam
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Novel naphthoquinone derivatives and their use for treating cardiovascular diseases and malignancies (BGN)
Scientific Contact: Yossef Granot
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NOVEL PEPTIDES FOR TREATING COCAINE ADDICTION AND PAIN (BIRAD)
The Problems1. Drug addiction is a scourge of both developed and less-developed societies. The economic impact of drug addiction includes direct treatment costs as well as lost productivity and crime. 2. Neuropathic pain is a chronic pain condition caused by a primary lesion or dysfunction in the ...
Scientific Contact: Gal Yadid
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Novel strategy for targeting glycosylated patterns on cancer cells using CAR T-cells (BIRAD)
The ProblemImmunotherapy has become a revolution in the area of cancer treatment. Compared to the traditional methods, such as invasive surgeries, radiation and chemotherapy, immunotherapy is more specific and less toxic to patients. Chimeric antigen receptor (CAR)-engineered T cell therapy is ...
Scientific Contact: Cyrille Cohen
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Novel Therapeutic System to Treat Osteoarthritis (Mor)
Background GAGs (glycoaminoglycans) are the most abundant polysaccharides which play important roles in many body systems. GAGs are major constituents of the extracellular matrix (ECM) of cartilage, skin, blood vessels, synovial fluid, bone and others. Their deficiency is associated with a wide ...
Scientific Contact: Dror Robinson
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NOVEL TOPICAL SMALL RNA MOLECULE AS TREATMENT FOR PSORIASIS (Tel Hashomer)
Novel Topical small RNA Molecule as Treatment for Psoriasis Prof. Sidi & Dr. Avni, Sheba Medical Center, Israel Categories Psoriasis, Topical Treatment , Novel Composition, autoimmune Disease Development Stage Preclinical efficacy Patent Status Pending THM Reference ...
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OAK cochleates: Method and composition for a delivery platform (Technion)
The present invention suggests the formation of cochleates from oligy-acyl-lysine (OAK) compound for adjuvants and drug delivery as a more efficient, safe and easy to manufacture. ...
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Oil Globule Protein and Uses Thereof (BGN)
Scientific Contact: Sammy Boussiba
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One molecule with several therapeutic modalities against cancer (BioRap)
One of the obstacles in clinical oncology is that tumors sometimes acquire resistance to therapy and spread. Throughout the years, various therapeutic agents have been developed aiming to directly target tumor cells or inhibit tumor-supporting cells in its microenvironment. The development of ...
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Optical logic gate (Technion)
Future digital communication systems are expected to be faster and capable of transferring larger amounts of data. As current electronically-based systems will not be able to handle these demands, alternative solutions are required. Optical networking is expected to provide faster throughput ...
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Optical tweezers (Technion)
New devices and technologies rely on “micro pumps” to transport fluids. Our technology allows beams of light to manipulate the local density of particles suspended in liquids or gases. It can be used to control the physical and chemical properties of the fluid, and to manipulate ...
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Optogenetics for the treatment of cardiac arrhythmias (BioRap)
Optogenetics approaches, utilizing light-sensitive proteins, have emerged as unique experimental paradigms to modulate neuronal excitability and have consequentially revolutionized neuroscience. The group of Dr. Lior Gepstein is developing similar strategies to also control cardiac-tissue ...
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Peptides and Binding Antibodies targeting EMMPRIN for the treatment of Cancer & Autoimmune Diseases (BioRap)
The identification of a specific epitope in EMMPRIN that has a role in the induction of both MMP-9 and VEGF, has brought about the development of two novel immunotherapy approached targeting EMMPRIN - A multiple antigenic peptide and a binding antibody. Macrophages heavily infiltrate solid ...
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Pharmceutical Composition and System for Permeabilizing Fetal Membranes (BGN)
Scientific Contact: Joseph Kost
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Piezoelectric-ferroelectric stack actuator and shape control algorithm (Technion)
Piezoelectric stack actuators are a common choice for micro- and nano-positioning systems. However, they are limited in terms of travel range (stroke). Our advanced piezoelectric-ferroelectric actuator has a travel range-to-length ratio up to six times greater than traditional piezoelectric stack ...
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Polysaccharide Sponges for Cell Culture and Transplantation (BGN)
Scientific Contact: Smadar Cohen
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Polyunsaturated Fatty acid Elongase Gene and Uses Thereof (BGN)
Scientific Contact: Zvi HaCohen
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