Technology Opportunities

BGN (42)
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BIRAD (5)
Mor (5)
Technion (25)
Tel Hashomer (13)
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Identification of Dietary Antioxidants which Protect Against Cardiovascular Diseases (BioRap)
BioRap Technologies and the Lipid Research Laboratory of the Rappaport Family Institute are offering collaboration for the identification of antioxidant and anti - atherogenic properties of nutritional antioxidants The lipid research laboratory, headed by Professor Michael Aviram, focuses its ...
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Iodine as antiseptic for dental use (BGN)
Scientific Contact: Amnon Sintov
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Light Activated Drug Delivery using Cell-Penetrating Peptides for Diagnostic and Therapeutic Applications (BGN)
Cell-penetrating peptides (CPPs) have been successfully used for intracellular delivery of a broad variety of cargoes including various nanoparticulate pharmaceutical carriers (liposomes, micelles, nanoparticles, polymer-conjugates). However the cationic nature of all CPP sequences and thus lack of ...
Scientific Contact: Ayelet David
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Liposomal Hemin for Anticancer Treatment (Tel Hashomer)
Liposomal Hemin for Anticancer Treatment Prof. Jonathan Leor, Head of the Cardiovascular Research Institute at Tel-Aviv University and Sheba Medical Center and Prof. Margalit Rimona, The Department of Biochemistry and Molecular Biology, Tel Aviv University THE NEED Myocardial infarction (MI) ...
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Long QT Syndrome, CPVT & ARVC: Personalized Medicine and Drug Development - Induced Pluripotent Stem Cells Derived Cardiomyocytes (BioRap)
Prof. Lior Gepstein's hiPSCs (human induced pluripotent stem cells) approach for modeling inherited cardiac disorders, such as Pompe glycogen storage disease, congenital long QT syndrome type II, CPVT and ARVC, has many implications in cardiovascular regenerative medicine, drug discovery, disease ...
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Long QT Syndrome, CPVT & Cradiomyopathies: Drug screening and toxicity testing by Induced Pluripotent Stem Cell-Derived Cardiomyocytes (BioRap)
An innovative platform for drug screening, toxicology testing and exploration of nevel means for treating severe cardiac pathologies, has been generated by Prof. Binah, focusing on inherited cardiac diseases such as Long Q-T Syndrome (LQTS), Catecholaminergic Polymorphic Ventricular Tachycardia ...
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Method and System for Electron Radiotherapy (BGN)
Scientific Contact: Itzhak Orion
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Method of suppressing disease severity of multiple sclerosis using chemokine CXC11 (Technion)
A method of treating an autoimmune disease such as Multiple Sclerosis is disclosed. The method comprises administering to a subject a ...
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Method of Treating Neurological Disorders (BGN)
Scientific Contact: Alon Friedman
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Methods and Compositions for Inhibiting the Nuclear Factor k-B Pathway (BGN)
Scientific Contact: Avi Golan
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Methods for Inhibiting Necrosis (BGN)
Scientific Contact: Ilana Nathan
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Microstructure control of ceramic matrix nanocomposites (Technion)
A method facilitating a way to obtain ceramic nanocomposites via a safe and very low cost process yielding ceramics with improved strengths and with a significantly improved Weibull modulus. The material also shows remarkable wear properties. Example applications include ceramic cutting tools, ...
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MinoGuard - Conquering Schizophrenia with Novel Combination Therapies (Mor)
BackgroundSchizophrenia is a chronic disorder that requires lifelong medication. While most of the available drugs are effective in remitting schizophrenia’s “positive symptoms” (hallucinations, delusions, agitation), even the best available drug is only partially effective in remitting ...
Scientific Contact: Hillik Levkovitz
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MULTI-EPITOPE CITRULLINATED PEPTIDE FOR TREATMENT OF RHEUMATOID ARTHRITIS (Tel Hashomer)
Multi-Epitope Citrullinated peptide for treatment of Rheumatoid Arthritis Howard Amital, Smadar Gertel and Yehuda Shoenfeld, Sheba Medical Center, Tel Hashomer Categories Novel Composition, Immune tolerance, arthritis , Drug, Inflamation Development Stage Pre-clinical Patent ...
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New Polymer-Peptide Conjugates for Targeting and Delivering Drugs to Tumor Vascular Endothelium (BGN)
Success in the treatment of cancer with chemotherapy is often limited by the non-specific toxicity of anticancer drugs. Current therapeutic approaches to the treatment of cancer are thus focused on developing novel delivery systems to increase the therapeutic efficacy of anticancer agents by ...
Scientific Contact: Ayelet David
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New Potential Molecules and Targets for Cancer Therapy (BioRap)
Professor Gera Neufeld, a member of the Rappaport Family Institute for Research in the Medical Sciences, Haifa, Israel, studies tumor angiogenesis and investigates the molecular mechanisms that contribute to the development and progression of cancer. Vascular endothelial growth factor (VEGF) ...
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Non-covalently corona-crosslinked polymeric micelles (Technion)
Polymeric micelles are a valuable nanotechnology for delivery of poorly water-soluble drugs. In this invention a novel kind of polymeric micelle has been developed formed by the self–assembly of graft copolymers synthesized by the hydrophobization of synthetic. These novel nanocarriers ...
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Novel PAR-1-based Therapeutic Compounds for Neuro-inflammatory Diseases (Tel Hashomer)
Joav Chapman and Efrat Shavit-Stein, Sheba Medical Center, Israel Abstract Many neurological diseases are known to be associated with increased inflammation and over activation of protease activated receptors (PAR) by protein factors of the coagulation cascade. We suggest a coagulation-based ...
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Novel Composition for the treatment of Multiple Myeloma (Tel Hashomer)
Novel Composition for the treatment of Multiple Myeloma Dr Merav Laibo , Sheba Medical Center Categories Novel Drug , Multiple Sclerosis Development Stage Preclinical Patent Status Three related patent applications(2011, 2013, 2014) Background and Technology Multiple myeloma ...
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Novel Compounds for the Treatment of Liver Fibrosis/Cirrhosis (Tel Hashomer)
Novel Compounds for the Treatment of Liver Fibrosis/Cirrhosis Prof. Ziv Ben-Ari and Dr. Michal Safran, Sheba Medical Center Categories Therapeutic Composition , Liver Fibrosis, Fibrosis, drug Development Stage Preclinical Patent Status Pending THM Reference 2016045 ...
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