Technology Opportunities

In vitro and in vivo animal models for stroke, Alzheimer's disease (AD), and multiple sclerosis (MS). Rapid screening method for selecting candidates with specific insulin-degrading enzyme inhibitor activity in Types I and II Diabetes. ...

Inhibition of IDE were suggested in the literature to be beneficial to both type I and type II diabetic. Nevertheless, currently there is no specific IDE inhibitor beside insulin itself or targeting Zink in the core of the enzymatic activity that might affect other enzymes. Recently, IDE has ...

Cerebrovascular dysfunction is a fundamental part of the pathology of several neurodegenerative diseases and rated as one of the most prominent cause for dementia. Cerebral amyloid angiopathy (CAA) results in intra-parenchymal and subarachnoid bleeding, which is caused by cerebrovascular ...

The Technology Multiple sclerosis (MS) is an autoimmune disease of the central nervous system characterized by damage to the neuronal myelin sheath, which results in different levels of muscle paralysis that can lead to neuronal death. In most MS mouse models, the neurologic damage mostly ...