Technology Opportunities

The invention provides methods for stabilization of mutant p53 in embryonic stem cells by interacting proteins, compositions comprising the same and uses thereof for treatment of various conditions associated with mut-p53, such as, cancer. Additional information can be provided upon ...

THE NEED Despite the overall good prognosis of luminal breast cancers, risk of recurrence rises substantially if the cancer had already metastasized to nearby lymph nodes by the time of diagnosis. While lymph node negative patients may benefit from endocrine therapy alone, the standard of care ...