Technology Opportunities

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3D tissue structures using differentiating embryonic stem cells (Technion)
Human embryonic stem (hES) cells hold promise as an unlimited source of cells for transplantation therapies. The present invention is a method for the control of hES cell proliferation and differentiation into complex, viable 3D tissue constructs. The invention describes the use of biodegradable ...
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3D vascularized pancreatic islets - for islets transplantation (Technion)
The present invention provides an advanced tissue-engineering technique for the development of 3D co-culture systems that reconstruct vascularization of pancreatic tissue ex-vivo. In this novel engineered 3D pancreatic model, isolated pancreatic islets can be co-cultured with endothelial cells. The ...
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A new drug and gene delivery system to the brain (Technion)
Though the brain has relatively high blood flow, it remains one of the least accessible organs for drug delivery due to the blood-brain barrier (BBB) and cerebrospinal fluid barrier, which separate the brain from its blood supply and control the movement of compounds in and out of the brain. Our ...
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A novel strategy for treating melanoma development and resistance (Technion)
The present technology describes the caspase-3/YAP module as a new target for the treatment of melanoma development and ...
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A pharmacological Trojan horse approach to eradicate multidrug-resistant cancer (Technion)
The present technology describes an efficient method to eradicate multidrug resistance (MDR) tumor cells via lysosomal photodestruction ...
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Adult stem cell-derived connective tissue progenitors for tissue engineering (Technion)
The present invention provides methods for generating and utilization of connective tissue progenitor cells from adult stem cells, successfully overcoming shortcomings of presently known configurations. Adult stem cells differentiate into connective tissue progenitor cells capable of being ...
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An antibody fragment capable of modulating multidrug resistance (Technion)
The present invention relates to an antibody fragment capable of binding to P-glycoprotein associated with multidrug resistant (MDR) cells. The present invention also relates to compositions and methods utilizing such an antibody fragment for inhibiting drug efflux activity in MDR cancer cells. ...
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Anti-nematode specific treatment based on cells fusion for agricultural use (Technion)
The present technology offers a new approach, using fusogene to treat nematodes infection and overcome the resistance appearance in a specific non-toxic ...
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Antimicrobial peptides and uses thereof (Technion)
A fragment of a virulent peptide named phenol- soluble modulin (PSM) having anti- bacterial ...
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Bacterial capture by resin-linked oligy-acyl-lysines (Technion)
The present technology relates to a method for filtration and concentration of bacterial contaminants from liquid media, by use of oligomers of acylated lysyls (OAKs) in their resin-linked form ...
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BENoC-bus enhancement network on chip (Technion)
Network on chip (NoC) is the future of VLSI interconnects. The technology enables improved chip performance in numerous aspects such as power consumption and data transfer rate. Several drawbacks are to be worked out to accelerate its acceptance as an industry standard. Our technology solves some ...
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Bifunctional antibiotics for targeting rRNA and resistance-causing enzymes (Technion)
Neomycin B is an important antibiotic, commonly used as a food-additive for agricultural purposes. As a result of antibiotic formulations having been used for several decades, resistance to antibiotics has been evolving. The present invention is a Neomycin B that has been modified by the addition ...
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Cancer multidrug resistance diagnostic method for personalize chemotherapy (Technion)
The present technology provides a quick and reliable test to identify multidrug resistance in cancer cells and personalize chemotherapeutic drug treatment. ...
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Casein micelles for encapsulation of hydrophobic compounds (Technion)
The present technology presents a novel harness casein-micelles (CM), which are natural nanocapsules of essential nutrients for the neonate, by incorporating nutraceuticals in their ...
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Casein particles encapsulating therapeutically active agents. (Technion)
The present technology describes a novel oral drug delivery system for drug resistance gastric cancers. Comprising a hydrophobic chemotherapeutic drug and a chemosensitizer entrapped within nanoparticles of beta casein (β-CN), which self-associates into micelles. ...
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Cell manipulation using nanoparticles and short laser pulses (Technion)
The present technology involves the use of nanoparticles and laser light to manipulate selected cells for cancer therapy, tissue regeneration and drug ...
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Cell-derived liposomes for drug delivery (Technion)
A major challenge facing cancer therapy is achieving specific cytotoxic effect towards cancer cells while sparing the healthy ones. This invention describes the development of an innovative targeted system for cancer therapy based on mesanchymal stem cell (MSC) derived liposomes. The engineered ...
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Combinations of corroles and statins (Technion)
High blood cholesterol level is a main and well established risk factor for the development of cardiovascular disease. Statins, inhibitors of cholesterol biosynthesis, are the leading drugs for reducing cholesterol levels and the most prescribed pharmaceuticals worldwide. We have created ...
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Compositions and Methods for Diagnosing and Treating an Inflammation (Technion)
A method of treating multiple sclerosis (MS) in a subject in need thereof, the method comprising administering to said subject a therapeutically effective amount of an isolated polypeptide comprising an antigen recognition ...
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Compositions and methods for drug delivery (Technion)
The present invention is of a hydrogel containing an immobilized, naturally-occurring protein drug carrier which may be used for sustained or controlled drug delivery applications. This hydrogel matrix can also be made to be biodegradable. Following this concept, a photopolymerizable hybrid ...
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