Technology Opportunities

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Minimally invasive, single–use, disposable device for repairing damaged eardrums - Tympanoplasty (Mor)
Name of Project: Tympanoplasty Device Inventors: Dr. Ariel Margulis, MD Medical Center: Meir Medical Center Field of Invention: Minimally invasive, single–use, disposable device for repairing damaged eardrums - tympanoplasty Technology: A medical device that enables the repair and promoting the ...
Scientific Contact: Ariel Margulis
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MinoGuard - Conquering Schizophrenia with Novel Combination Therapies (Mor)
BackgroundSchizophrenia is a chronic disorder that requires lifelong medication. While most of the available drugs are effective in remitting schizophrenia’s “positive symptoms” (hallucinations, delusions, agitation), even the best available drug is only partially effective in remitting ...
Scientific Contact: Hillik Levkovitz
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MULTI-EPITOPE CITRULLINATED PEPTIDE FOR TREATMENT OF RHEUMATOID ARTHRITIS (Tel Hashomer)
Multi-Epitope Citrullinated peptide for treatment of Rheumatoid Arthritis Howard Amital, Smadar Gertel and Yehuda Shoenfeld, Sheba Medical Center, Tel Hashomer Categories Novel Composition, Immune tolerance, arthritis , Drug, Inflamation Development Stage Pre-clinical Patent ...
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Multi-Pump-Pass Fiber Based Lasers and Amplifiers (BGN)
Scientific Contact: Amiel Ishaaya
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Multifocal ultrasound and its effect on biological membranes (Technion)
Ultrasound has been extensively used for imaging for 60 years, and is now being studied towards clinical therapeutic application. Understanding the basic mechanism of its function is critical. Technion Researchers propose a hypothesis whereby ultrasound induces bubble formation in the ...
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NatureInhale - For the Treatment of Recurrent Throat Tonsilitis (Mor)
Background Nearly every child experiences at least one episode of throat inflammation (pharingotonsillitis), generating no less than 8 million office visits each year by children, adolescents and young adults aged up to 24 years. 40% of cases have a bacterial etiology (usually group A ...
Scientific Contact: Yossi Rakover
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New Polymer-Peptide Conjugates for Targeting and Delivering Drugs to Tumor Vascular Endothelium (BGN)
Success in the treatment of cancer with chemotherapy is often limited by the non-specific toxicity of anticancer drugs. Current therapeutic approaches to the treatment of cancer are thus focused on developing novel delivery systems to increase the therapeutic efficacy of anticancer agents by ...
Scientific Contact: Ayelet David
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New Potential Molecules and Targets for Cancer Therapy (BioRap)
Professor Gera Neufeld, a member of the Rappaport Family Institute for Research in the Medical Sciences, Haifa, Israel, studies tumor angiogenesis and investigates the molecular mechanisms that contribute to the development and progression of cancer. Vascular endothelial growth factor (VEGF) ...
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New Technique for Repairing Ischemic Mitral Valve Regurgitation and Remodeling of the left ventricle (Mor)
Clinical Background: Ischemic Mitral valve regurgitation is a challenging medical problem that is caused by and results from REMODELING of the Ischemic left ventricle. Remodeling leads to: 1. Displacement of Papillary muscles 2. Annular dilatation that prevents normal coaptation 3. Tethering of ...
Scientific Contact: Amnon Zlotnik
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Non Invasive pterygium excision and peeling (Tel Hashomer)
Non Invasive pterygium excision and peeling Ygal Rotenstreich, Sheba Medical Center, Israel Categories Medical Device, Ophthalmology, Pterygium Development Stage Preclinical Patent Status Pending THM Reference 201527 Abstract A pterygium is fleshy tissue that grows in a ...
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Non-contact holographic stimulation technology for vision restoration devices (Technion)
A unique technology for direct optical stimulation of neurons has been developed in the Technion. This Technology could have diverse applications in the field of advanced neurological devices and particularly the development of next-generation vision restoration devices. The new, non-contact ...
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Non-Invasive Sampling of Amniotic Fluid (BGN)
Making an effort to minimize the risk for genetic birth abnormalities is a naturally strong parental need, while governments encourage it mainly for economical reasons. In more than 90% of the cases of detection of chromosomal abnormalities in the fetus, a decision to terminate pregnancy is being ...
Scientific Contact: Joseph Kost
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Noninvasive imaging of flowing blood cells (Technion)
This novel method of noninvasive imaging, which allows visualization of the morphology and dynamics of circulating cells, avoids the need to handle specimens and bypasses the need for exogenous labeling of cells, with potentially toxic dyes. Additional advantages include shortened wait-time, ...
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Novel PAR-1-based Therapeutic Compounds for Neuro-inflammatory Diseases (Tel Hashomer)
Joav Chapman and Efrat Shavit-Stein, Sheba Medical Center, Israel Abstract Many neurological diseases are known to be associated with increased inflammation and over activation of protease activated receptors (PAR) by protein factors of the coagulation cascade. We suggest a coagulation-based ...
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Novel antimicrobial agents (Technion)
Over the past decades, advancement in the field of antimicrobial agents had reduced dramatically illness and death due to infectious diseases. However, almost all the prominent infection causing bacterial strains have developed resistance to antibiotics. The present invention relates to novel ...
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Novel Composition for the treatment of Multiple Myeloma (Tel Hashomer)
Novel Composition for the treatment of Multiple Myeloma Dr Merav Laibo , Sheba Medical Center Categories Novel Drug , Multiple Sclerosis Development Stage Preclinical Patent Status Three related patent applications(2011, 2013, 2014) Background and Technology Multiple myeloma ...
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Novel Compounds for the Treatment of Liver Fibrosis/Cirrhosis (Tel Hashomer)
Novel Compounds for the Treatment of Liver Fibrosis/Cirrhosis Prof. Ziv Ben-Ari and Dr. Michal Safran, Sheba Medical Center Categories Therapeutic Composition , Liver Fibrosis, Fibrosis, drug Development Stage Preclinical Patent Status Pending THM Reference 2016045 ...
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NOVEL COMPOUNDS TO TREAT ANTIBIOTIC-RESISTANT CLINICAL ISOLATED PATHOGENS (Tel Hashomer)
Novel compounds to treat antibiotic-resistant clinical isolated pathogens Israel Nisan, Noa Tejman Yarden, Yaakov Davidov, Galia Rahav , Sheba Medical Center Categories Antibiotics, composition, drug resistant, infection disaeses, Development Stage Pre-clinical Patent ...
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NOVEL DELIVERY VEHICLE FOR CELL TRANSFECTION (BIRAD)
The ProblemNanoparticles can be manufactured with tunable size, shape and surface as well as biological activity. Their role as nanocarriers is well established. While many nanoparticles are stable as an aqueous colloid, ferro fluid, they maintain an insufficient active surface and are limited in ...
Scientific Contact: Jean-Paul Lellouche
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Novel Guide Device for Temporomandibular Joint Arthroscopy (Tel Hashomer)
Novel Guide Device for Temporomandibular Joint Arthroscopy Dr. Waseem A. Abboud, Sheba Medical Center Categories Maxillofacial Surgery, Medical Surgery Guided device Development Stage Preclinical, prototype design Patent Status Pending THM Reference 2015043 Abstract The ...
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